Cargando…

The tumour suppressor miR-34c targets MET in prostate cancer cells

BACKGROUND: The microRNA, miR-34c, is a well-established regulator of tumour suppression. It is downregulated in most forms of cancers and inhibits malignant growth by repressing genes involved in processes such as proliferation, anti-apoptosis, stemness, and migration. We have previously reported d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hagman, Z, Haflidadottir, B S, Ansari, M, Persson, M, Bjartell, A, Edsjö, A, Ceder, Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778300/ https://www.ncbi.nlm.nih.gov/pubmed/23922103 http://dx.doi.org/10.1038/bjc.2013.449

Ejemplares similares

miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients
por: Hagman, Z, et al.
Publicado: (2013)

Upregulation of miR-96 Enhances Cellular Proliferation of Prostate Cancer Cells through FOXO1
por: Haflidadóttir, Benedikta S., et al.
Publicado: (2013)

The loss of the tumour-suppressor miR-145 results in the shorter disease-free survival of prostate cancer patients
por: Avgeris, M, et al.
Publicado: (2013)

miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215
por: White, N M A, et al.
Publicado: (2011)

miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer
por: Chiyomaru, T, et al.
Publicado: (2010)

Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors
por: Xu, Y, et al.
Publicado: (2012)

miR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells
por: Higashi, T, et al.
Publicado: (2015)

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours
por: Gits, C M M, et al.
Publicado: (2013)

The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer
por: Yoshino, H, et al.
Publicado: (2011)

EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205
por: Massoner, P, et al.
Publicado: (2014)

Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer
por: Kalimutho, M, et al.
Publicado: (2011)

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
por: Meng, Xiaodan, et al.
Publicado: (2015)

The expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers
por: Muir, Brian, et al.
Publicado: (2015)

RNA helicase DHX15 acts as a tumour suppressor in glioma
por: Ito, Shingo, et al.
Publicado: (2017)

MicroRNAs miR-371-3 in serum as diagnostic tools in the management of testicular germ cell tumours
por: Dieckmann, K-P, et al.
Publicado: (2012)

Clinical significance of miR-144-ZFX axis in disseminated tumour cells in bone marrow in gastric cancer cases
por: Akiyoshi, S, et al.
Publicado: (2012)

miR-29a/b/c function as invasion suppressors for gliomas by targeting CDC42 and predict the prognosis of patients
por: Shi, Cuijuan, et al.
Publicado: (2017)

miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC)
por: Kikkawa, N, et al.
Publicado: (2010)

FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role
por: Bullock, M D, et al.
Publicado: (2013)

MicroRNA expression signature of castration-resistant prostate cancer: the microRNA-221/222 cluster functions as a tumour suppressor and disease progression marker
por: Goto, Yusuke, et al.
Publicado: (2015)

The von Hippel–Lindau tumour suppressor gene: uncovering the expression of the pVHL172 isoform
por: Chesnel, F, et al.
Publicado: (2015)

Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma
por: Aigelsreiter, A, et al.
Publicado: (2013)

miR-21 and miR-155 are associated with mitotic activity and lesion depth of borderline melanocytic lesions
por: Grignol, V, et al.
Publicado: (2011)

Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer
por: Miyamoto, K, et al.
Publicado: (2016)

Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer
por: Huh, J H, et al.
Publicado: (2013)

Downregulation of miR-302c and miR-520c by 1,25(OH)2D3 treatment enhances the susceptibility of tumour cells to natural killer cell-mediated cytotoxicity
por: Min, D, et al.
Publicado: (2013)

The FOXD3/miR-214/MED19 axis suppresses tumour growth and metastasis in human colorectal cancer
por: He, G Y, et al.
Publicado: (2016)

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer
por: Rao, S R, et al.
Publicado: (2017)

Regulation of the T-box transcription factor Tbx3 by the tumour suppressor microRNA-206 in breast cancer
por: Amir, Sumaira, et al.
Publicado: (2016)

FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling
por: Cai, Jian, et al.
Publicado: (2015)

Downregulated miR-646 in clear cell renal carcinoma correlated with tumour metastasis by targeting the nin one binding protein (NOB1)
por: Li, W, et al.
Publicado: (2014)

Role of multifunctional transcription factor TFII-I and putative tumour suppressor DBC1 in cell cycle and DNA double strand damage repair
por: Tanikawa, M, et al.
Publicado: (2013)

miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer
por: Zhang, J, et al.
Publicado: (2012)

Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma
por: Miyamoto, M, et al.
Publicado: (2011)

ARID1B, a member of the human SWI/SNF chromatin remodeling complex, exhibits tumour-suppressor activities in pancreatic cancer cell lines
por: Khursheed, M, et al.
Publicado: (2013)

MET phosphorylation predicts poor outcome in small cell lung carcinoma and its inhibition blocks HGF-induced effects in MET mutant cell lines
por: Arriola, E, et al.
Publicado: (2011)

Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game
por: Basanta, D, et al.
Publicado: (2012)

Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells
por: Dixon, K M, et al.
Publicado: (2013)

Impaired access of lymphocytes to neoplastic prostate tissue is associated with neoangiogenesis in the tumour site
por: Fedida, S, et al.
Publicado: (2007)

The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
por: Ragnum, H B, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qki6eks42b8p8b8qnobr2gcamc