Synthesis of the reported structure of piperazirum using a nitro-Mannich reaction as the key stereochemical determining step

Piperazirum, isolated from Arum palaestinum Boiss, was originally assigned as r-3,c-5-diisobutyl-c-6-isopropylpiperazin-2-one. The reported structure was synthesised diastereoselectively using a key nitro-Mannich reaction to set up the C5/C6 relative stereochemistry. The structure was unambiguously...

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Detalles Bibliográficos
Autores principales: Anderson, James C, Kalogirou, Andreas S, Porter, Michael J, Tizzard, Graham J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778392/
https://www.ncbi.nlm.nih.gov/pubmed/24062836
http://dx.doi.org/10.3762/bjoc.9.200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778392/
https://www.ncbi.nlm.nih.gov/pubmed/24062836
http://dx.doi.org/10.3762/bjoc.9.200

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