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Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process

A Fe(acac)(3)-catalyzed decarboxylative coupling of 2-(aryl)vinyl carboxylic acids with cycloalkanes was developed by using DTBP as an oxidant through a radical process. This reaction tolerates a wide range of substrates, and products are obtained in good to excellent yields (71–95%). The reaction a...

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Detalles Bibliográficos
Autores principales: Zhao, Jiancan, Fang, Hong, Han, Jianlin, Pan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778410/
https://www.ncbi.nlm.nih.gov/pubmed/24062833
http://dx.doi.org/10.3762/bjoc.9.197
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author Zhao, Jiancan
Fang, Hong
Han, Jianlin
Pan, Yi
author_facet Zhao, Jiancan
Fang, Hong
Han, Jianlin
Pan, Yi
author_sort Zhao, Jiancan
collection PubMed
description A Fe(acac)(3)-catalyzed decarboxylative coupling of 2-(aryl)vinyl carboxylic acids with cycloalkanes was developed by using DTBP as an oxidant through a radical process. This reaction tolerates a wide range of substrates, and products are obtained in good to excellent yields (71–95%). The reaction also shows excellent stereoselectivity, and only trans-isomers are obtained.
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spelling pubmed-37784102013-09-23 Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process Zhao, Jiancan Fang, Hong Han, Jianlin Pan, Yi Beilstein J Org Chem Full Research Paper A Fe(acac)(3)-catalyzed decarboxylative coupling of 2-(aryl)vinyl carboxylic acids with cycloalkanes was developed by using DTBP as an oxidant through a radical process. This reaction tolerates a wide range of substrates, and products are obtained in good to excellent yields (71–95%). The reaction also shows excellent stereoselectivity, and only trans-isomers are obtained. Beilstein-Institut 2013-08-21 /pmc/articles/PMC3778410/ /pubmed/24062833 http://dx.doi.org/10.3762/bjoc.9.197 Text en Copyright © 2013, Zhao et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Zhao, Jiancan
Fang, Hong
Han, Jianlin
Pan, Yi
Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
title Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
title_full Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
title_fullStr Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
title_full_unstemmed Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
title_short Iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
title_sort iron-catalyzed decarboxylative alkenylation of cycloalkanes with arylvinyl carboxylic acids via a radical process
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778410/
https://www.ncbi.nlm.nih.gov/pubmed/24062833
http://dx.doi.org/10.3762/bjoc.9.197
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AT hanjianlin ironcatalyzeddecarboxylativealkenylationofcycloalkaneswitharylvinylcarboxylicacidsviaaradicalprocess
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