Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols

A gold(I)-catalysed reaction of allylic alcohols and phenols produces chromans regioselectively via a one-pot Friedel–Crafts allylation/intramolecular hydroalkoxylation sequence. The reaction is mild, practical and tolerant of a wide variety of substituents on the phenol.

Detalles Bibliográficos
Autores principales: Coutant, Eloi, Young, Paul C, Barker, Graeme, Lee, Ai-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778418/
https://www.ncbi.nlm.nih.gov/pubmed/24062845
http://dx.doi.org/10.3762/bjoc.9.209
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author Coutant, Eloi
Young, Paul C
Barker, Graeme
Lee, Ai-Lan
author_facet Coutant, Eloi
Young, Paul C
Barker, Graeme
Lee, Ai-Lan
author_sort Coutant, Eloi
collection PubMed
description A gold(I)-catalysed reaction of allylic alcohols and phenols produces chromans regioselectively via a one-pot Friedel–Crafts allylation/intramolecular hydroalkoxylation sequence. The reaction is mild, practical and tolerant of a wide variety of substituents on the phenol.
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spelling pubmed-37784182013-09-23 Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols Coutant, Eloi Young, Paul C Barker, Graeme Lee, Ai-Lan Beilstein J Org Chem Full Research Paper A gold(I)-catalysed reaction of allylic alcohols and phenols produces chromans regioselectively via a one-pot Friedel–Crafts allylation/intramolecular hydroalkoxylation sequence. The reaction is mild, practical and tolerant of a wide variety of substituents on the phenol. Beilstein-Institut 2013-09-04 /pmc/articles/PMC3778418/ /pubmed/24062845 http://dx.doi.org/10.3762/bjoc.9.209 Text en Copyright © 2013, Coutant et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Coutant, Eloi
Young, Paul C
Barker, Graeme
Lee, Ai-Lan
Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
title Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
title_full Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
title_fullStr Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
title_full_unstemmed Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
title_short Gold(I)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
title_sort gold(i)-catalysed one-pot synthesis of chromans using allylic alcohols and phenols
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778418/
https://www.ncbi.nlm.nih.gov/pubmed/24062845
http://dx.doi.org/10.3762/bjoc.9.209
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