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Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm

INTRODUCTION: The Enterococcus faecalis biofilm in the root canal makes it difficult to be eradicated by the conventional irrigants with no toxicity to the tissues. Hence, plant products with least side effects are explored for their use as irrigants in the root canal therapy. AIM: To evaluate and c...

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Autores principales: Subbiya, Arunajatesan, Mahalakshmi, Krishnan, Pushpangadan, Sivan, Padmavathy, Kesavaram, Vivekanandan, Paramasivam, Sukumaran, Vridhachalam Ganapathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778630/
https://www.ncbi.nlm.nih.gov/pubmed/24082577
http://dx.doi.org/10.4103/0972-0707.117507
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author Subbiya, Arunajatesan
Mahalakshmi, Krishnan
Pushpangadan, Sivan
Padmavathy, Kesavaram
Vivekanandan, Paramasivam
Sukumaran, Vridhachalam Ganapathy
author_facet Subbiya, Arunajatesan
Mahalakshmi, Krishnan
Pushpangadan, Sivan
Padmavathy, Kesavaram
Vivekanandan, Paramasivam
Sukumaran, Vridhachalam Ganapathy
author_sort Subbiya, Arunajatesan
collection PubMed
description INTRODUCTION: The Enterococcus faecalis biofilm in the root canal makes it difficult to be eradicated by the conventional irrigants with no toxicity to the tissues. Hence, plant products with least side effects are explored for their use as irrigants in the root canal therapy. AIM: To evaluate and compare the antibacterial efficacy of Mangifera indica L. kernel (mango kernel) and Ocimum sanctum L. leaves (tulsi) extracts with conventional irrigants (5% sodium hypochlorite (NaOCl) and 2% chlorhexidine) against E. faecalis dentinal biofilm. MATERIALS AND METHODS: Agar diffusion and broth microdilution assay was performed with the herbal extracts and conventional irrigants (2% chlorhexidine and 5% NaOCl) against E. faecalis planktonic cells. The assay was extended onto 3 week E. faecalis dentinal biofilm. RESULTS: Significant reduction of colony forming units (CFU)/mL was observed for the herbal groups and the antibacterial activity of the herbal groups was at par with 5% NaOCl. CONCLUSIONS: The antibacterial activity of these herbal extracts is found to be comparable with that of conventional irrigants both on the biofilm and planktonic counterparts.
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spelling pubmed-37786302013-09-30 Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm Subbiya, Arunajatesan Mahalakshmi, Krishnan Pushpangadan, Sivan Padmavathy, Kesavaram Vivekanandan, Paramasivam Sukumaran, Vridhachalam Ganapathy J Conserv Dent Original Article INTRODUCTION: The Enterococcus faecalis biofilm in the root canal makes it difficult to be eradicated by the conventional irrigants with no toxicity to the tissues. Hence, plant products with least side effects are explored for their use as irrigants in the root canal therapy. AIM: To evaluate and compare the antibacterial efficacy of Mangifera indica L. kernel (mango kernel) and Ocimum sanctum L. leaves (tulsi) extracts with conventional irrigants (5% sodium hypochlorite (NaOCl) and 2% chlorhexidine) against E. faecalis dentinal biofilm. MATERIALS AND METHODS: Agar diffusion and broth microdilution assay was performed with the herbal extracts and conventional irrigants (2% chlorhexidine and 5% NaOCl) against E. faecalis planktonic cells. The assay was extended onto 3 week E. faecalis dentinal biofilm. RESULTS: Significant reduction of colony forming units (CFU)/mL was observed for the herbal groups and the antibacterial activity of the herbal groups was at par with 5% NaOCl. CONCLUSIONS: The antibacterial activity of these herbal extracts is found to be comparable with that of conventional irrigants both on the biofilm and planktonic counterparts. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3778630/ /pubmed/24082577 http://dx.doi.org/10.4103/0972-0707.117507 Text en Copyright: © Journal of Conservative Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Subbiya, Arunajatesan
Mahalakshmi, Krishnan
Pushpangadan, Sivan
Padmavathy, Kesavaram
Vivekanandan, Paramasivam
Sukumaran, Vridhachalam Ganapathy
Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm
title Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm
title_full Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm
title_fullStr Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm
title_full_unstemmed Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm
title_short Antibacterial efficacy of Mangifera indica L. kernel and Ocimum sanctum L. leaves against Enterococcus faecalis dentinal biofilm
title_sort antibacterial efficacy of mangifera indica l. kernel and ocimum sanctum l. leaves against enterococcus faecalis dentinal biofilm
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778630/
https://www.ncbi.nlm.nih.gov/pubmed/24082577
http://dx.doi.org/10.4103/0972-0707.117507
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