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Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

The covalent attachment of the protein ubiquitin to intracellular proteins by a process known as ubiquitylation regulates almost all major cellular systems, predominantly by regulating protein turnover. Ubiquitylation requires the co-ordinated action of three enzymes termed E1, E2 and E3, and typica...

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Detalles Bibliográficos
Autores principales: Tatham, Michael H., Plechanovová, Anna, Jaffray, Ellis G., Salmen, Helena, Hay, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778709/
https://www.ncbi.nlm.nih.gov/pubmed/23560854
http://dx.doi.org/10.1042/BJ20130244

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