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Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid
A 65-year-old woman with bullous pemphigoid presented with fever and several red-purple nodular subcutaneous lesions on both lower legs 1 week after starting treatment with azathioprine (AZA). Biopsy of a skin nodule was compatible with erythema nodosum (EN) and hypersensitivity reaction to AZA was...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778797/ https://www.ncbi.nlm.nih.gov/pubmed/24082202 http://dx.doi.org/10.4103/0019-5154.117332 |
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author | Vargas-Hitos, Jose Antonio Sabio, Jose Mario Tercedor, Jesús Navarrete-Navarrete, Nuria Jiménez-Alonso, Juan |
author_facet | Vargas-Hitos, Jose Antonio Sabio, Jose Mario Tercedor, Jesús Navarrete-Navarrete, Nuria Jiménez-Alonso, Juan |
author_sort | Vargas-Hitos, Jose Antonio |
collection | PubMed |
description | A 65-year-old woman with bullous pemphigoid presented with fever and several red-purple nodular subcutaneous lesions on both lower legs 1 week after starting treatment with azathioprine (AZA). Biopsy of a skin nodule was compatible with erythema nodosum (EN) and hypersensitivity reaction to AZA was suspected. AZA was subsequently discontinued, observing complete remission of fever and EN within 2 weeks. This case highlights the importance of recognizing EN as a possible manifestation of hypersensitivity reaction to AZA. |
format | Online Article Text |
id | pubmed-3778797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37787972013-09-30 Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid Vargas-Hitos, Jose Antonio Sabio, Jose Mario Tercedor, Jesús Navarrete-Navarrete, Nuria Jiménez-Alonso, Juan Indian J Dermatol E-Case Report A 65-year-old woman with bullous pemphigoid presented with fever and several red-purple nodular subcutaneous lesions on both lower legs 1 week after starting treatment with azathioprine (AZA). Biopsy of a skin nodule was compatible with erythema nodosum (EN) and hypersensitivity reaction to AZA was suspected. AZA was subsequently discontinued, observing complete remission of fever and EN within 2 weeks. This case highlights the importance of recognizing EN as a possible manifestation of hypersensitivity reaction to AZA. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3778797/ /pubmed/24082202 http://dx.doi.org/10.4103/0019-5154.117332 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | E-Case Report Vargas-Hitos, Jose Antonio Sabio, Jose Mario Tercedor, Jesús Navarrete-Navarrete, Nuria Jiménez-Alonso, Juan Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid |
title | Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid |
title_full | Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid |
title_fullStr | Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid |
title_full_unstemmed | Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid |
title_short | Erythema Nodosum as Azathioprine Hypersensitivity Reaction in a Patient with Bullous Pemphigoid |
title_sort | erythema nodosum as azathioprine hypersensitivity reaction in a patient with bullous pemphigoid |
topic | E-Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778797/ https://www.ncbi.nlm.nih.gov/pubmed/24082202 http://dx.doi.org/10.4103/0019-5154.117332 |
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