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Exploiting tumor epigenetics to improve oncolytic virotherapy
Oncolytic viruses (OVs) comprise a versatile and multi-mechanistic therapeutic platform in the growing arsenal of anticancer biologics. These replicating therapeutics find favorable conditions in the tumor niche, characterized among others by increased metabolism, reduced anti-tumor/antiviral immuni...
Autores principales: | Forbes, Nicole E., Abdelbary, Hesham, Lupien, Mathieu, Bell, John C., Diallo, Jean-Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778850/ https://www.ncbi.nlm.nih.gov/pubmed/24062768 http://dx.doi.org/10.3389/fgene.2013.00184 |
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