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Local Arginase 1 Activity Is Required for Cutaneous Wound Healing

Chronic nonhealing wounds in the elderly population are associated with a prolonged and excessive inflammatory response, which is widely hypothesized to impede healing. Previous studies have linked alterations in local L-arginine metabolism, principally mediated by the enzymes arginase (Arg) and ind...

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Detalles Bibliográficos
Autores principales: Campbell, Laura, Saville, Charis R, Murray, Peter J, Cruickshank, Sheena M, Hardman, Matthew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778883/
https://www.ncbi.nlm.nih.gov/pubmed/23552798
http://dx.doi.org/10.1038/jid.2013.164