Cargando…
c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
Although the sebaceous gland (SG) plays an important role in skin function, the mechanisms regulating SG differentiation and carcinoma formation are poorly understood. We previously reported that c-MYC overexpression stimulates SG differentiation. We now demonstrate roles for the androgen receptor (...
Autores principales: | Cottle, Denny L., Kretzschmar, Kai, Schweiger, Pawel J., Quist, Sven R., Gollnick, Harald P., Natsuga, Ken, Aoyagi, Satoru, Watt, Fiona M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778892/ https://www.ncbi.nlm.nih.gov/pubmed/23403291 http://dx.doi.org/10.1016/j.celrep.2013.01.013 |
Ejemplares similares
-
BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions
por: Kretzschmar, Kai, et al.
Publicado: (2014) -
Mutant Lef1 controls Gata6 in sebaceous gland development and cancer
por: Oulès, Bénédicte, et al.
Publicado: (2019) -
The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
por: Kretzschmar, Kai, et al.
Publicado: (2015) -
p53 activity contributes to defective interfollicular epidermal differentiation in hyperproliferative murine skin
por: Cottle, D.L., et al.
Publicado: (2015) -
Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation
por: Berta, Melanie A, et al.
Publicado: (2010)