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Lipidomic profiling in Crohn's disease: Abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition
Crohn's disease is a chronic inflammatory condition largely affecting the terminal ileum and large bowel. A contributing cause is the failure of an adequate acute inflammatory response as a result of impaired secretion of pro-inflammatory cytokines by macrophages. This defective secretion arise...
Autores principales: | Sewell, Gavin W., Hannun, Yusuf A., Han, Xianlin, Koster, Grielof, Bielawski, Jacek, Goss, Victoria, Smith, Philip J., Rahman, Farooq Z., Vega, Roser, Bloom, Stuart L., Walker, Ann P., Postle, Anthony D., Segal, Anthony W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778899/ https://www.ncbi.nlm.nih.gov/pubmed/22728312 http://dx.doi.org/10.1016/j.biocel.2012.06.016 |
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