Non-Secreted Clusterin Isoforms Are Translated in Rare Amounts from Distinct Human mRNA Variants and Do Not Affect Bax-Mediated Apoptosis or the NF-κB Signaling Pathway

Clusterin, also known as apolipoprotein J, is expressed from a variety of tissues and implicated in pathological disorders such as neurodegenerative diseases, ischemia and cancer. In contrast to secretory clusterin (sCLU), which acts as an extracellular chaperone, the synthesis, subcellular localiza...

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Detalles Bibliográficos
Autores principales: Prochnow, Hans, Gollan, Rene, Rohne, Philipp, Hassemer, Matthias, Koch-Brandt, Claudia, Baiersdörfer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779157/
https://www.ncbi.nlm.nih.gov/pubmed/24073260
http://dx.doi.org/10.1371/journal.pone.0075303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779157/
https://www.ncbi.nlm.nih.gov/pubmed/24073260
http://dx.doi.org/10.1371/journal.pone.0075303

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