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Cathepsin L Plays a Role in Quinolinic Acid-Induced NF-Κb Activation and Excitotoxicity in Rat Striatal Neurons

The present study seeks to investigate the role of cathepsin L in glutamate receptor-induced transcription factor nuclear factor-kappa B (NF-κB) activation and excitotoxicity in rats striatal neurons. Stereotaxic administration of the N-methyl-d-aspartate (NMDA) receptor agonist Quinolinic acid (QA)...

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Detalles Bibliográficos
Autores principales: Wang, Yan-Ru, Qin, Shu, Han, Rong, Wu, Jun-Chao, Liang, Zhong-Qin, Qin, Zheng-Hong, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779166/
https://www.ncbi.nlm.nih.gov/pubmed/24073275
http://dx.doi.org/10.1371/journal.pone.0075702