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Lipid Metabolites Enhance Secretion Acting on SNARE Microdomains and Altering the Extent and Kinetics of Single Release Events in Bovine Adrenal Chromaffin Cells
Lipid molecules such as arachidonic acid (AA) and sphingolipid metabolites have been implicated in modulation of neuronal and endocrine secretion. Here we compare the effects of these lipids on secretion from cultured bovine chromaffin cells. First, we demonstrate that exogenous sphingosine and AA i...
Autores principales: | García-Martínez, Virginia, Villanueva, José, Torregrosa-Hetland, Cristina J., Bittman, Robert, Higdon, Ashlee, Darley-Usmar, Victor M., Davletov, Bazbek, Gutiérrez, Luis M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779176/ https://www.ncbi.nlm.nih.gov/pubmed/24073281 http://dx.doi.org/10.1371/journal.pone.0075845 |
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