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Common Genetic Variations in Patched1 (PTCH1) Gene and Risk of Hirschsprung Disease in the Han Chinese Population

Hirschsprung disease (HSCR) is the most frequent genetic cause of congenital intestinal obstruction with an incidence of 1:5000 live births. In a pathway-based epistasis analysis of data generated by genome-wide association study on HSCR, specific genotype of Patched 1 (PTCH1) has been linked to an...

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Detalles Bibliográficos
Autores principales:	Wang, Yang, Wang, Jun, Pan, Weihua, Zhou, Ying, Xiao, Yongtao, Zhou, Kejun, Wen, Jie, Yu, Tingxi, Cai, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779180/ https://www.ncbi.nlm.nih.gov/pubmed/24073265 http://dx.doi.org/10.1371/journal.pone.0075407

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