Differential Host Response, Rather Than Early Viral Replication Efficiency, Correlates with Pathogenicity Caused by Influenza Viruses

Influenza viruses exhibit large, strain-dependent differences in pathogenicity in mammalian hosts. Although the characteristics of severe disease, including uncontrolled viral replication, infection of the lower airway, and highly inflammatory cytokine responses have been extensively documented, the...

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Detalles Bibliográficos
Autores principales: Askovich, Peter S., Sanders, Catherine J., Rosenberger, Carrie M., Diercks, Alan H., Dash, Pradyot, Navarro, Garnet, Vogel, Peter, Doherty, Peter C., Thomas, Paul G., Aderem, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779241/
https://www.ncbi.nlm.nih.gov/pubmed/24073225
http://dx.doi.org/10.1371/journal.pone.0074863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779241/
https://www.ncbi.nlm.nih.gov/pubmed/24073225
http://dx.doi.org/10.1371/journal.pone.0074863

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