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Differential Host Response, Rather Than Early Viral Replication Efficiency, Correlates with Pathogenicity Caused by Influenza Viruses
Influenza viruses exhibit large, strain-dependent differences in pathogenicity in mammalian hosts. Although the characteristics of severe disease, including uncontrolled viral replication, infection of the lower airway, and highly inflammatory cytokine responses have been extensively documented, the...
Autores principales: | Askovich, Peter S., Sanders, Catherine J., Rosenberger, Carrie M., Diercks, Alan H., Dash, Pradyot, Navarro, Garnet, Vogel, Peter, Doherty, Peter C., Thomas, Paul G., Aderem, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779241/ https://www.ncbi.nlm.nih.gov/pubmed/24073225 http://dx.doi.org/10.1371/journal.pone.0074863 |
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