The B7-1 Cytoplasmic Tail Enhances Intracellular Transport and Mammalian Cell Surface Display of Chimeric Proteins in the Absence of a Linear ER Export Motif

Membrane-tethered proteins (mammalian surface display) are increasingly being used for novel therapeutic and biotechnology applications. Maximizing surface expression of chimeric proteins on mammalian cells is important for these applications. We show that the cytoplasmic domain from the B7-1 antige...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Chieh, Chen, Bing-Mae, Lu, Wei-Cheng, Su, Chien-I, Prijovich, Zeljko M., Chung, Wen-Chuan, Wu, Pei-Yu, Chen, Kai-Chuan, Lee, I-Chiao, Juan, Ting-Yi, Roffler, Steve R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779271/
https://www.ncbi.nlm.nih.gov/pubmed/24073236
http://dx.doi.org/10.1371/journal.pone.0075084

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