A TSPO ligand is protective in a mouse model of multiple sclerosis

Local production of neurosteroids such as progesterone and allopregnanolone confers neuroprotection in central nervous system (CNS) inflammatory diseases. The mitochondrial translocator protein (TSPO) performs a rate-limiting step in the conversion of cholesterol to pregnenolone and its steroid deri...

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Detalles Bibliográficos
Autores principales: Daugherty, Daniel J, Selvaraj, Vimal, Chechneva, Olga V, Liu, Xiao-Bo, Pleasure, David E, Deng, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779450/
https://www.ncbi.nlm.nih.gov/pubmed/23681668
http://dx.doi.org/10.1002/emmm.201202124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779450/
https://www.ncbi.nlm.nih.gov/pubmed/23681668
http://dx.doi.org/10.1002/emmm.201202124

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