The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival

Pigment cells and neuronal cells both are derived from the neural crest. Here, we describe the Pit-Oct-Unc (POU) domain transcription factor Brn3a, normally involved in neuronal development, to be frequently expressed in melanoma, but not in melanocytes and nevi. RNAi-mediated silencing of Brn3a str...

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Detalles Bibliográficos
Autores principales: Hohenauer, Tobias, Berking, Carola, Schmidt, Andreas, Haferkamp, Sebastian, Senft, Daniela, Kammerbauer, Claudia, Fraschka, Sabine, Graf, Saskia Anna, Irmler, Martin, Beckers, Johannes, Flaig, Michael, Aigner, Achim, Höbel, Sabrina, Hoffmann, Franziska, Hermeking, Heiko, Rothenfusser, Simon, Endres, Stefan, Ruzicka, Thomas, Besch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779452/
https://www.ncbi.nlm.nih.gov/pubmed/23666755
http://dx.doi.org/10.1002/emmm.201201862

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