Indoleamine 2,3-dioxygenase Activity Contributes to Local Immune Suppression in the Skin Expressing Human Papillomavirus Oncoprotein E7

Chronic infection of anogenital epithelium with human papillomavirus (HPV) promotes development of cancer. Many pathogens evoke immunosuppressive mechanisms to enable persistent infection. We have previously shown that grafted skin expressing HPV16 E7 oncoprotein from a keratin-14 promoter (K14E7) i...

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Detalles Bibliográficos
Autores principales: Mittal, D, Kassianos, AJ, Tran, LS, Bergot, AS, Gosmann, C, Hofmann, J, Blumenthal, A, Leggatt, GR, Frazer, IH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779505/
https://www.ncbi.nlm.nih.gov/pubmed/23652797
http://dx.doi.org/10.1038/jid.2013.222

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