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Pramipexole Reduces Phosphorylation of α-Synuclein at Serine-129

α-Synuclein is a central component of the pathogenesis of Parkinson’s disease (PD). Phosphorylation at serine-129 represents an important post-translational modification and constitutes the major form of the protein in Lewy bodies. Several kinases have been implicated in the phosphorylation of α-syn...

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Detalles Bibliográficos
Autores principales: Chau, Kai-Yin, Cooper, J. Mark, Schapira, Anthony Henry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779594/
https://www.ncbi.nlm.nih.gov/pubmed/23681749
http://dx.doi.org/10.1007/s12031-013-0030-8