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Metabolic modulation of chromatin: implications for DNA repair and genomic integrity
The maintenance of genomic integrity in response to DNA damage is tightly linked to controlled changes in the damage-proximal chromatin environment. Many of the chromatin modifying enzymes involved in DNA repair depend on metabolic intermediates as cofactors, suggesting that changes in cellular meta...
Autores principales: | Liu, Jinping, Kim, Jeongkyu, Oberdoerffer, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779809/ https://www.ncbi.nlm.nih.gov/pubmed/24065984 http://dx.doi.org/10.3389/fgene.2013.00182 |
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