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Anti-inflammatory effects of budesonide in human lung fibroblast are independent of histone deacetylase 2
OBJECTIVE AND DESIGN: Reduced expression of histone deacetylase 2 (HDAC2) in alveolar macrophages and epithelial cells may account for reduced response of chronic obstructive pulmonary disease (COPD) patients to glucocorticoids. HDAC2 expression and its role in mediating glucocorticoid effects on fi...
Autores principales: | Wang, Xingqi, Nelson, Amy, Weiler, Zachary M, Patil, Amol, Sato, Tadashi, Kanaji, Nobuhiro, Nakanishi, Masanori, Michalski, Joel, Farid, Maha, Basma, Hesham, LeVan, Tricia D, Miller-Larsson, Anna, Wieslander, Elisabet, Muller, Kai-Christian, Holz, Olaf, Magnussen, Helgo, Rabe, Klaus F, Liu, Xiangde, Rennard, Stephen I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780291/ https://www.ncbi.nlm.nih.gov/pubmed/24062615 http://dx.doi.org/10.2147/JIR.S43736 |
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