Cargando…

Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions

Recent interest in the early course of schizophrenia accentuated altered cognition prior to the onset. Ultrahigh risk (UHR) individuals with attenuated positive symptoms and transient psychotic episodes demonstrate neurocognitive deficits across multiple domains such as memory, executive functioning...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaytseva, Yulia, Korsakova, Natalya, Agius, Mark, Gurovich, Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780553/
https://www.ncbi.nlm.nih.gov/pubmed/24089689
http://dx.doi.org/10.1155/2013/819587
_version_ 1782285320006402048
author Zaytseva, Yulia
Korsakova, Natalya
Agius, Mark
Gurovich, Isaac
author_facet Zaytseva, Yulia
Korsakova, Natalya
Agius, Mark
Gurovich, Isaac
author_sort Zaytseva, Yulia
collection PubMed
description Recent interest in the early course of schizophrenia accentuated altered cognition prior to the onset. Ultrahigh risk (UHR) individuals with attenuated positive symptoms and transient psychotic episodes demonstrate neurocognitive deficits across multiple domains such as memory, executive functioning, and processing speed which are consistent with similar disturbances identified in patients with a first episode of schizophrenia. Cognitive remediation (CR) approaches representing a broad set of activities are aimed to restore or improve cognitive functioning. CR proved to be effective in modulating the cognitive dysfunction in schizophrenia but is rarely used in ultrahigh risk individuals. From the clinical prospective, a better understanding of cognitive functioning in at-risk states is essential for the development of optimal early intervention models. In the review, we highlight the intervention targets, notably the specific cognitive deficits in at risk individuals which preceed the transition to psychosis and emphasize the need of the additional studies using CR approaches in UHR group aiming to enhance cognition and therefore mediate functional improvement.
format Online
Article
Text
id pubmed-3780553
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-37805532013-10-02 Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions Zaytseva, Yulia Korsakova, Natalya Agius, Mark Gurovich, Isaac Biomed Res Int Review Article Recent interest in the early course of schizophrenia accentuated altered cognition prior to the onset. Ultrahigh risk (UHR) individuals with attenuated positive symptoms and transient psychotic episodes demonstrate neurocognitive deficits across multiple domains such as memory, executive functioning, and processing speed which are consistent with similar disturbances identified in patients with a first episode of schizophrenia. Cognitive remediation (CR) approaches representing a broad set of activities are aimed to restore or improve cognitive functioning. CR proved to be effective in modulating the cognitive dysfunction in schizophrenia but is rarely used in ultrahigh risk individuals. From the clinical prospective, a better understanding of cognitive functioning in at-risk states is essential for the development of optimal early intervention models. In the review, we highlight the intervention targets, notably the specific cognitive deficits in at risk individuals which preceed the transition to psychosis and emphasize the need of the additional studies using CR approaches in UHR group aiming to enhance cognition and therefore mediate functional improvement. Hindawi Publishing Corporation 2013 2013-09-05 /pmc/articles/PMC3780553/ /pubmed/24089689 http://dx.doi.org/10.1155/2013/819587 Text en Copyright © 2013 Yulia Zaytseva et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zaytseva, Yulia
Korsakova, Natalya
Agius, Mark
Gurovich, Isaac
Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions
title Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions
title_full Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions
title_fullStr Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions
title_full_unstemmed Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions
title_short Neurocognitive Functioning in Schizophrenia and during the Early Phases of Psychosis: Targeting Cognitive Remediation Interventions
title_sort neurocognitive functioning in schizophrenia and during the early phases of psychosis: targeting cognitive remediation interventions
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780553/
https://www.ncbi.nlm.nih.gov/pubmed/24089689
http://dx.doi.org/10.1155/2013/819587
work_keys_str_mv AT zaytsevayulia neurocognitivefunctioninginschizophreniaandduringtheearlyphasesofpsychosistargetingcognitiveremediationinterventions
AT korsakovanatalya neurocognitivefunctioninginschizophreniaandduringtheearlyphasesofpsychosistargetingcognitiveremediationinterventions
AT agiusmark neurocognitivefunctioninginschizophreniaandduringtheearlyphasesofpsychosistargetingcognitiveremediationinterventions
AT gurovichisaac neurocognitivefunctioninginschizophreniaandduringtheearlyphasesofpsychosistargetingcognitiveremediationinterventions