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Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets

Quinolinic acid (QUIN), a neuroactive metabolite of the kynurenine pathway, is normally presented in nanomolar concentrations in human brain and cerebrospinal fluid (CSF) and is often implicated in the pathogenesis of a variety of human neurological diseases. QUIN is an agonist of N-methyl-D-asparta...

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Detalles Bibliográficos
Autores principales: Lugo-Huitrón, Rafael, Ugalde Muñiz, Perla, Pineda, Benjamin, Pedraza-Chaverrí, José, Ríos, Camilo, Pérez-de la Cruz, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780648/
https://www.ncbi.nlm.nih.gov/pubmed/24089628
http://dx.doi.org/10.1155/2013/104024