Cargando…
Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets
Quinolinic acid (QUIN), a neuroactive metabolite of the kynurenine pathway, is normally presented in nanomolar concentrations in human brain and cerebrospinal fluid (CSF) and is often implicated in the pathogenesis of a variety of human neurological diseases. QUIN is an agonist of N-methyl-D-asparta...
Autores principales: | Lugo-Huitrón, Rafael, Ugalde Muñiz, Perla, Pineda, Benjamin, Pedraza-Chaverrí, José, Ríos, Camilo, Pérez-de la Cruz, Verónica |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780648/ https://www.ncbi.nlm.nih.gov/pubmed/24089628 http://dx.doi.org/10.1155/2013/104024 |
Ejemplares similares
-
Kynurenines with Neuroactive and Redox Properties: Relevance to Aging and Brain Diseases
por: Reyes Ocampo, Jazmin, et al.
Publicado: (2014) -
On the Antioxidant Properties of L-Kynurenine: An Efficient ROS Scavenger and Enhancer of Rat Brain Antioxidant Defense
por: Ramírez Ortega, Daniela, et al.
Publicado: (2021) -
Alternative kynurenic acid synthesis routes studied in the rat cerebellum
por: Blanco Ayala, Tonali, et al.
Publicado: (2015) -
Quinolinic Acid: Neurotoxin or Oxidative Stress Modulator?
por: Kubicova, Lenka, et al.
Publicado: (2013) -
Quinolinic Acid, an Endogenous Molecule Combining Excitotoxicity, Oxidative Stress and Other Toxic Mechanisms
por: Pérez-De La Cruz, Verónica, et al.
Publicado: (2012)