Cavin-3 dictates the balance between ERK and Akt signaling

Cavin-3 is a tumor suppressor protein of unknown function. Using both in vivo and in vitro approaches, we show that cavin-3 dictates the balance between ERK and Akt signaling. Loss of cavin-3 increases Akt signaling at the expense of ERK, while gain of cavin-3 increases ERK signaling at the expense...

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Detalles Bibliográficos
Autores principales: Hernandez, Victor J, Weng, Jian, Ly, Peter, Pompey, Shanica, Dong, Hongyun, Mishra, Lopa, Schwarz, Margaret, Anderson, Richard GW, Michaely, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780650/
https://www.ncbi.nlm.nih.gov/pubmed/24069528
http://dx.doi.org/10.7554/eLife.00905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780650/
https://www.ncbi.nlm.nih.gov/pubmed/24069528
http://dx.doi.org/10.7554/eLife.00905

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