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An algorithm for chemical genomic profiling that minimizes batch effects: bucket evaluations
BACKGROUND: Chemical genomics is an interdisciplinary field that combines small molecule perturbation with traditional genomics to understand gene function and to study the mode(s) of drug action. A benefit of chemical genomic screens is their breadth; each screen can capture the sensitivity of comp...
Autores principales: | Shabtai, Daniel, Giaever, Guri, Nislow, Corey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780717/ https://www.ncbi.nlm.nih.gov/pubmed/23009392 http://dx.doi.org/10.1186/1471-2105-13-245 |
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