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A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman

Cushing's syndrome is characterized by central obesity, fatigability, weakness, amenorrhea, hirsutism, edema, hypertension, impaired glucose tolerance, and osteoporosis due to excessive production of steroids. Cushing's syndrome is an important cause of secondary osteoporosis. Patients wit...

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Autores principales: Han, Ju Young, Lee, Jungjin, Kim, Gyung Eun, Yeo, Jin Yeob, Kim, So hun, Nam, Moonsuk, Kim, Yong Seong, Hong, SeongBin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780926/
https://www.ncbi.nlm.nih.gov/pubmed/24524047
http://dx.doi.org/10.11005/jbm.2012.19.2.153
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author Han, Ju Young
Lee, Jungjin
Kim, Gyung Eun
Yeo, Jin Yeob
Kim, So hun
Nam, Moonsuk
Kim, Yong Seong
Hong, SeongBin
author_facet Han, Ju Young
Lee, Jungjin
Kim, Gyung Eun
Yeo, Jin Yeob
Kim, So hun
Nam, Moonsuk
Kim, Yong Seong
Hong, SeongBin
author_sort Han, Ju Young
collection PubMed
description Cushing's syndrome is characterized by central obesity, fatigability, weakness, amenorrhea, hirsutism, edema, hypertension, impaired glucose tolerance, and osteoporosis due to excessive production of steroids. Cushing's syndrome is an important cause of secondary osteoporosis. Patients with Cushing's syndrome have a high incidence of osteoporotic fractures. At least, 30-50% of patients with Cushing's syndrome experience fractures, particularly in the vertebral body. And it is consistent with the 50% prevalence of osteoporosis in patients with Cushing's syndrome. However, reports of multiple pathological fractures in young patients with Cushing's syndrome are rare. Thus, we describe the case of a 26-year-old woman with Cushing's syndrome accompanied with recurrent multiple osteoporotic fractures and being treated by parathyroid hormone. Careful consideration for the possibility of Cushing's syndrome will be necessary in case of young patients with a spontaneous multiple compression fractures in spine.
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spelling pubmed-37809262014-02-12 A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman Han, Ju Young Lee, Jungjin Kim, Gyung Eun Yeo, Jin Yeob Kim, So hun Nam, Moonsuk Kim, Yong Seong Hong, SeongBin J Bone Metab Case Report Cushing's syndrome is characterized by central obesity, fatigability, weakness, amenorrhea, hirsutism, edema, hypertension, impaired glucose tolerance, and osteoporosis due to excessive production of steroids. Cushing's syndrome is an important cause of secondary osteoporosis. Patients with Cushing's syndrome have a high incidence of osteoporotic fractures. At least, 30-50% of patients with Cushing's syndrome experience fractures, particularly in the vertebral body. And it is consistent with the 50% prevalence of osteoporosis in patients with Cushing's syndrome. However, reports of multiple pathological fractures in young patients with Cushing's syndrome are rare. Thus, we describe the case of a 26-year-old woman with Cushing's syndrome accompanied with recurrent multiple osteoporotic fractures and being treated by parathyroid hormone. Careful consideration for the possibility of Cushing's syndrome will be necessary in case of young patients with a spontaneous multiple compression fractures in spine. The Korean Society for Bone and Mineral Research 2012-11 2012-11-16 /pmc/articles/PMC3780926/ /pubmed/24524047 http://dx.doi.org/10.11005/jbm.2012.19.2.153 Text en Copyright © 2012 The Korean Society for Bone and Mineral Research http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/).
spellingShingle Case Report
Han, Ju Young
Lee, Jungjin
Kim, Gyung Eun
Yeo, Jin Yeob
Kim, So hun
Nam, Moonsuk
Kim, Yong Seong
Hong, SeongBin
A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
title A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
title_full A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
title_fullStr A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
title_full_unstemmed A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
title_short A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
title_sort case of cushing syndrome diagnosed by recurrent pathologic fractures in a young woman
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780926/
https://www.ncbi.nlm.nih.gov/pubmed/24524047
http://dx.doi.org/10.11005/jbm.2012.19.2.153
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