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Identification of New Drug Targets and Resistance Mechanisms in Mycobacterium tuberculosis

Identification of new drug targets is vital for the advancement of drug discovery against Mycobacterium tuberculosis, especially given the increase of resistance worldwide to first- and second-line drugs. Because traditional target-based screening has largely proven unsuccessful for antibiotic disco...

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Detalles Bibliográficos
Autores principales:	Ioerger, Thomas R., O’Malley, Theresa, Liao, Reiling, Guinn, Kristine M., Hickey, Mark J., Mohaideen, Nilofar, Murphy, Kenan C., Boshoff, Helena I. M., Mizrahi, Valerie, Rubin, Eric J., Sassetti, Christopher M., Barry, Clifton E., Sherman, David R., Parish, Tanya, Sacchettini, James C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781026/ https://www.ncbi.nlm.nih.gov/pubmed/24086479 http://dx.doi.org/10.1371/journal.pone.0075245

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