Toll-Like Receptor 4 Deficiency Accelerates the Development of Insulin-Deficient Diabetes in Non-Obese Diabetic Mice

BACKGROUND/OBJECTIVE: Toll-like receptors (TLR) mediate the recognition of microbial constituents and stress-induced endogenous ligands by the immune system. They may also be involved in the maintenance or break down of tolerance against autologous antigens. The aim of our investigation was to study...

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Detalles Bibliográficos
Autores principales: Gülden, Elke, Ihira, Masaru, Ohashi, Atsushi, Reinbeck, Anna Lena, Freudenberg, Marina A., Kolb, Hubert, Burkart, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781027/
https://www.ncbi.nlm.nih.gov/pubmed/24086519
http://dx.doi.org/10.1371/journal.pone.0075385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781027/
https://www.ncbi.nlm.nih.gov/pubmed/24086519
http://dx.doi.org/10.1371/journal.pone.0075385

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