Increase in Net Activity of Serine Proteinases but Not Gelatinases after Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects

We tested the hypothesis that activation of the innate immune response induces an imbalance in the proteolytic homeostasis in the peripheral airways of healthy subjects, towards excess serine or gelatinase proteinase activity. During bronchoscopy, 18 healthy human subjects underwent intra-bronchial...

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Detalles Bibliográficos
Autores principales: Smith, Margaretha E., Bozinovski, Steven, Malmhäll, Carina, Sjöstrand, Margareta, Glader, Pernilla, Venge, Per, Hiemstra, Pieter S., Anderson, Gary P., Lindén, Anders, Qvarfordt, Ingemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781029/
https://www.ncbi.nlm.nih.gov/pubmed/24086430
http://dx.doi.org/10.1371/journal.pone.0075032

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