Microglial Cells Are Involved in the Susceptibility of NADPH Oxidase Knockout Mice to 6-Hydroxy-Dopamine-Induced Neurodegeneration

We explored the impact of Nox-2 in modulating inflammatory-mediated microglial responses in the 6-hydroxydopamine (6-OHDA)-induced Parkinson’s disease (PD) model. Nox1 and Nox2 gene expression were found to increase in striatum, whereas a marked increase of Nox2 expression was observed in substantia...

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Detalles Bibliográficos
Autores principales: Hernandes, Marina S., Santos, Graziella D. R., Café-Mendes, Cecília C., Lima, Larissa S., Scavone, Cristoforo, Munhoz, Carolina D., Britto, Luiz R. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781051/
https://www.ncbi.nlm.nih.gov/pubmed/24086556
http://dx.doi.org/10.1371/journal.pone.0075532

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