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A VLP Library of C-Terminally Truncated Hepatitis B Core Proteins: Correlation of RNA Encapsidation with a Th1/Th2 Switch in the Immune Responses of Mice

An efficient pBR327- and Ptrp-based E. coli expression system was used to generate a large-scale library of virus like particles (VLP) formed by recombinant hepatitis B virus (HBV) core (HBc) protein derivatives. To construct the library, the gene of HBc protein of the genotype D/subtype ayw2 virus...

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Detalles Bibliográficos
Autores principales: Sominskaya, Irina, Skrastina, Dace, Petrovskis, Ivars, Dishlers, Andris, Berza, Ieva, Mihailova, Maria, Jansons, Juris, Akopjana, Inara, Stahovska, Irina, Dreilina, Dzidra, Ose, Velta, Pumpens, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781094/
https://www.ncbi.nlm.nih.gov/pubmed/24086668
http://dx.doi.org/10.1371/journal.pone.0075938

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