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Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation

One factor which may be important for determining proper lesion creation during atrial ablation is catheter-endocardial contact. Little information is available that relates geometric contact, depth and angle, to ablation lesion formation. We present an electrothermal computer model of ablation that...

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Detalles Bibliográficos
Autores principales: Gallagher, Neal, Fear, Elise C., Byrd, Israel A., Vigmond, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781109/
https://www.ncbi.nlm.nih.gov/pubmed/24086275
http://dx.doi.org/10.1371/journal.pone.0073242
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author Gallagher, Neal
Fear, Elise C.
Byrd, Israel A.
Vigmond, Edward J.
author_facet Gallagher, Neal
Fear, Elise C.
Byrd, Israel A.
Vigmond, Edward J.
author_sort Gallagher, Neal
collection PubMed
description One factor which may be important for determining proper lesion creation during atrial ablation is catheter-endocardial contact. Little information is available that relates geometric contact, depth and angle, to ablation lesion formation. We present an electrothermal computer model of ablation that calculated lesion volume and temperature development over time. The Pennes bioheat equation was coupled to a quasistatic electrical problem to investigate the effect of catheter penetration depth, as well as incident catheter angle as may occur in practice. Biological experiments were performed to verify the modelling of electrical phenomena. Results show that for deeply penetrating tips, acute catheter angles reduced the rate of temperature buildup, allowing larger lesions to form before temperatures elevated excessively. It was also found that greater penetration did not lead to greater transmurality of lesions. We conclude that catheter contact angle plays a significant role in lesion formation, and the time course must be considered. This is clinically relevant because proper identification and prediction of geometric contact variables could improve ablation efficacy.
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spelling pubmed-37811092013-10-01 Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation Gallagher, Neal Fear, Elise C. Byrd, Israel A. Vigmond, Edward J. PLoS One Research Article One factor which may be important for determining proper lesion creation during atrial ablation is catheter-endocardial contact. Little information is available that relates geometric contact, depth and angle, to ablation lesion formation. We present an electrothermal computer model of ablation that calculated lesion volume and temperature development over time. The Pennes bioheat equation was coupled to a quasistatic electrical problem to investigate the effect of catheter penetration depth, as well as incident catheter angle as may occur in practice. Biological experiments were performed to verify the modelling of electrical phenomena. Results show that for deeply penetrating tips, acute catheter angles reduced the rate of temperature buildup, allowing larger lesions to form before temperatures elevated excessively. It was also found that greater penetration did not lead to greater transmurality of lesions. We conclude that catheter contact angle plays a significant role in lesion formation, and the time course must be considered. This is clinically relevant because proper identification and prediction of geometric contact variables could improve ablation efficacy. Public Library of Science 2013-09-23 /pmc/articles/PMC3781109/ /pubmed/24086275 http://dx.doi.org/10.1371/journal.pone.0073242 Text en © 2013 Gallagher et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Gallagher, Neal
Fear, Elise C.
Byrd, Israel A.
Vigmond, Edward J.
Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation
title Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation
title_full Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation
title_fullStr Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation
title_full_unstemmed Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation
title_short Contact Geometry Affects Lesion Formation in Radio-Frequency Cardiac Catheter Ablation
title_sort contact geometry affects lesion formation in radio-frequency cardiac catheter ablation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781109/
https://www.ncbi.nlm.nih.gov/pubmed/24086275
http://dx.doi.org/10.1371/journal.pone.0073242
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