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The Nociceptin/Orphanin FQ Receptor Antagonist UFP-101 Reduces Microvascular Inflammation to Lipopolysaccharide In Vivo

Microvascular inflammation occurs during sepsis and the endogenous opioid-like peptide nociceptin/orphanin FQ (N/OFQ) is known to regulate inflammation. This study aimed to determine the inflammatory role of N/OFQ and its receptor NOP (ORL1) within the microcirculation, along with anti-inflammatory...

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Detalles Bibliográficos
Autores principales:	Brookes, Zoë L. S., Stedman, Emily N., Brown, Nicola J., Hebbes, Christopher P., Guerrini, Remo, Calo, Girolamo, Reilly, Charles S., Lambert, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781147/ https://www.ncbi.nlm.nih.gov/pubmed/24086402 http://dx.doi.org/10.1371/journal.pone.0074943

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