Polyalanine Repeat Polymorphism in RUNX2 Is Associated with Site-Specific Fracture in Post-Menopausal Females

Runt related transcription factor 2 (RUNX2) is a key regulator of osteoblast differentiation. Several variations within the RUNX2 gene have been found to be associated with significant changes in BMD, which is a major risk factor for fracture. In this study we report that an 18 bp deletion within th...

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Detalles Bibliográficos
Autores principales: Morrison, Nigel A., Stephens, Alexandre S., Osato, Motomi, Pasco, Julie A., Fozzard, Nicolette, Stein, Gary S., Polly, Patsie, Griffiths, Lyn R., Nicholson, Geoff C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781152/
https://www.ncbi.nlm.nih.gov/pubmed/24086263
http://dx.doi.org/10.1371/journal.pone.0072740

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