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The Hypoxia-Inducible Transcription Factor ZNF395 Is Controlled by IĸB Kinase-Signaling and Activates Genes Involved in the Innate Immune Response and Cancer
Activation of the hypoxia inducible transcription factor HIF and the NF-ĸB pathway promotes inflammation-mediated tumor progression. The cellular transcription factor ZNF395 has repeatedly been found overexpressed in various human cancers, particularly in response to hypoxia, implying a functional r...
Autores principales: | Jordanovski, Darko, Herwartz, Christine, Pawlowski, Anna, Taute, Stefanie, Frommolt, Peter, Steger, Gertrud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781154/ https://www.ncbi.nlm.nih.gov/pubmed/24086395 http://dx.doi.org/10.1371/journal.pone.0074911 |
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