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Mammalian DNA demethylation: Multiple faces and upstream regulation

DNA cytosine methylation is a reversible epigenetic mark regulating gene expression. Aberrant methylation profiles are concomitant with developmental defects and cancer. Numerous studies in the past decade have identified enzymes and pathways responsible for active DNA demethylation both on a genome...

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Detalles Bibliográficos
Autor principal: Schomacher, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781186/
https://www.ncbi.nlm.nih.gov/pubmed/23803967
http://dx.doi.org/10.4161/epi.24977