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Mammalian DNA demethylation: Multiple faces and upstream regulation
DNA cytosine methylation is a reversible epigenetic mark regulating gene expression. Aberrant methylation profiles are concomitant with developmental defects and cancer. Numerous studies in the past decade have identified enzymes and pathways responsible for active DNA demethylation both on a genome...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781186/ https://www.ncbi.nlm.nih.gov/pubmed/23803967 http://dx.doi.org/10.4161/epi.24977 |