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C/EBPa controls acquisition and maintenance of adult hematopoietic stem cell quiescence

In blood, transcription factor C/EBPa is essential for myeloid differentiation and has been implicated in regulating self-renewal of fetal liver (FL) hematopoietic stem cells (HSCs). However, its function in adult HSCs has remained unknown. Here, using an inducible knockout model we found that C/EBP...

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Detalles Bibliográficos
Autores principales: Ye, Min, Zhang, Hong, Amabile, Giovanni, Yang, Henry, Staber, Philipp B., Zhang, Pu, Levantini, Elena, Alberich-Jordà, Meritxell, Zhang, Junyan, Kawasaki, Akira, Tenen, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781213/
https://www.ncbi.nlm.nih.gov/pubmed/23502316
http://dx.doi.org/10.1038/ncb2698