Downregulation of Beclin1 and Impairment of Autophagy in a Small Population of Colorectal Cancer

BACKGROUND: Autophagy is a highly conserved mechanism for degradation and recycling of long-lived proteins and damaged organelle to maintain cell homeostasis. Deregulation of autophagy has been associated with tumorigenesis. Beclin 1 is an essential autophagy protein and its upregulation has been ob...

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Detalles Bibliográficos
Autores principales: Chen, Zhihong, Li, Yanchun, Zhang, Chi, Yi, Hongmei, Wu, Chang, Wang, Junpu, Liu, Yuwu, Tan, Jieqiong, Wen, Jifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781302/
https://www.ncbi.nlm.nih.gov/pubmed/23812859
http://dx.doi.org/10.1007/s10620-013-2732-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781302/
https://www.ncbi.nlm.nih.gov/pubmed/23812859
http://dx.doi.org/10.1007/s10620-013-2732-8

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