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Downregulation of Beclin1 and Impairment of Autophagy in a Small Population of Colorectal Cancer
BACKGROUND: Autophagy is a highly conserved mechanism for degradation and recycling of long-lived proteins and damaged organelle to maintain cell homeostasis. Deregulation of autophagy has been associated with tumorigenesis. Beclin 1 is an essential autophagy protein and its upregulation has been ob...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781302/ https://www.ncbi.nlm.nih.gov/pubmed/23812859 http://dx.doi.org/10.1007/s10620-013-2732-8 |