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C-C chemokine receptor-7 mediated endocytosis of antibody cargoes into intact cells

The C–C chemokine receptor-7 (CCR7) is a G protein coupled receptor that has a role in leukocyte homing, but that is also expressed in aggressive tumor cells. Preclinical research supports that CCR7 is a valid target in oncology. In view of the increasing availability of therapeutic monoclonal antib...

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Detalles Bibliográficos
Autores principales:	Charest-Morin, Xavier, Pépin, Rémy, Gagné-Henley, Angélique, Morissette, Guillaume, Lodge, Robert, Marceau, François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781320/ https://www.ncbi.nlm.nih.gov/pubmed/24068998 http://dx.doi.org/10.3389/fphar.2013.00122

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