Combination Pravastatin and Valsartan Treatment Has Additive Beneficial Effects to Simultaneously Improve Both Metabolic and Cardiovascular Phenotypes Beyond That of Monotherapy With Either Drug in Patients With Primary Hypercholesterolemia

Statin and angiotensin II type 1 receptor blocker therapy improves endothelial dysfunction using distinct mechanisms. We evaluated simultaneous vascular and metabolic responses to pravastatin and valsartan therapy, alone or in combination, in hypercholesterolemic patients. Forty-eight hypercholester...

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Detalles Bibliográficos
Autores principales: Koh, Kwang Kon, Lim, Soo, Choi, Hanul, Lee, Yonghee, Han, Seung Hwan, Lee, Kyounghoon, Oh, Pyung Chun, Sakuma, Ichiro, Shin, Eak Kyun, Quon, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781478/
https://www.ncbi.nlm.nih.gov/pubmed/23863812
http://dx.doi.org/10.2337/db13-0566

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