Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

Dysfunction of the blood-brain barrier (BBB) is a primary characteristic of experimental autoimmune encephalomyelitis (EAE), an experimental model of multiple sclerosis (MS). Matrine (MAT), a quinolizidine alkaloid derived from the herb Radix Sophorae Flave, has been recently found to suppress clini...

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Detalles Bibliográficos
Autores principales: Zhang, Su, Kan, Quan-Cheng, Xu, Yuming, Zhang, Guang-Xian, Zhu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781841/
https://www.ncbi.nlm.nih.gov/pubmed/24194630
http://dx.doi.org/10.1155/2013/736085

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