The Autophagy Inhibitor Verteporfin Moderately Enhances the Antitumor Activity of Gemcitabine in a Pancreatic Ductal Adenocarcinoma Model

Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to chemotherapy. It has been described as requiring elevated autophagy for growth and inhibiting autophagy has been proposed as a treatment strategy. To date, all preclinical reports and clinical trials investigating pharmacological inhibit...

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Detalles Bibliográficos
Autores principales: Donohue, Elizabeth, Thomas, Anitha, Maurer, Norbert, Manisali, Irina, Zeisser-Labouebe, Magali, Zisman, Natalia, Anderson, Hilary J., Ng, Sylvia S. W., Webb, Murray, Bally, Marcel, Roberge, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781989/
https://www.ncbi.nlm.nih.gov/pubmed/24069069
http://dx.doi.org/10.7150/jca.7030

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