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Myeloid-derived suppressor cells, age and cancer
We have recently discovered that the levels of circulating myeloid-derived suppressor cells, which are associated with an impaired T-cell proliferation and produce high amounts of reactive oxygen species, increase with age and are elevated in individuals in remission from cancer. Herein, potential m...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782016/ https://www.ncbi.nlm.nih.gov/pubmed/24073368 http://dx.doi.org/10.4161/onci.24754 |
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author | Bowdish, Dawn ME |
author_facet | Bowdish, Dawn ME |
author_sort | Bowdish, Dawn ME |
collection | PubMed |
description | We have recently discovered that the levels of circulating myeloid-derived suppressor cells, which are associated with an impaired T-cell proliferation and produce high amounts of reactive oxygen species, increase with age and are elevated in individuals in remission from cancer. Herein, potential mechanisms underpinning these observations are discussed. |
format | Online Article Text |
id | pubmed-3782016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-37820162013-09-26 Myeloid-derived suppressor cells, age and cancer Bowdish, Dawn ME Oncoimmunology Author's View We have recently discovered that the levels of circulating myeloid-derived suppressor cells, which are associated with an impaired T-cell proliferation and produce high amounts of reactive oxygen species, increase with age and are elevated in individuals in remission from cancer. Herein, potential mechanisms underpinning these observations are discussed. Landes Bioscience 2013-07-01 2013-04-30 /pmc/articles/PMC3782016/ /pubmed/24073368 http://dx.doi.org/10.4161/onci.24754 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Author's View Bowdish, Dawn ME Myeloid-derived suppressor cells, age and cancer |
title | Myeloid-derived suppressor cells, age and cancer |
title_full | Myeloid-derived suppressor cells, age and cancer |
title_fullStr | Myeloid-derived suppressor cells, age and cancer |
title_full_unstemmed | Myeloid-derived suppressor cells, age and cancer |
title_short | Myeloid-derived suppressor cells, age and cancer |
title_sort | myeloid-derived suppressor cells, age and cancer |
topic | Author's View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782016/ https://www.ncbi.nlm.nih.gov/pubmed/24073368 http://dx.doi.org/10.4161/onci.24754 |
work_keys_str_mv | AT bowdishdawnme myeloidderivedsuppressorcellsageandcancer |