Cargando…

Myeloid-derived suppressor cells, age and cancer

We have recently discovered that the levels of circulating myeloid-derived suppressor cells, which are associated with an impaired T-cell proliferation and produce high amounts of reactive oxygen species, increase with age and are elevated in individuals in remission from cancer. Herein, potential m...

Descripción completa

Detalles Bibliográficos
Autor principal: Bowdish, Dawn ME
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782016/
https://www.ncbi.nlm.nih.gov/pubmed/24073368
http://dx.doi.org/10.4161/onci.24754
_version_ 1782285507575676928
author Bowdish, Dawn ME
author_facet Bowdish, Dawn ME
author_sort Bowdish, Dawn ME
collection PubMed
description We have recently discovered that the levels of circulating myeloid-derived suppressor cells, which are associated with an impaired T-cell proliferation and produce high amounts of reactive oxygen species, increase with age and are elevated in individuals in remission from cancer. Herein, potential mechanisms underpinning these observations are discussed.
format Online
Article
Text
id pubmed-3782016
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Landes Bioscience
record_format MEDLINE/PubMed
spelling pubmed-37820162013-09-26 Myeloid-derived suppressor cells, age and cancer Bowdish, Dawn ME Oncoimmunology Author's View We have recently discovered that the levels of circulating myeloid-derived suppressor cells, which are associated with an impaired T-cell proliferation and produce high amounts of reactive oxygen species, increase with age and are elevated in individuals in remission from cancer. Herein, potential mechanisms underpinning these observations are discussed. Landes Bioscience 2013-07-01 2013-04-30 /pmc/articles/PMC3782016/ /pubmed/24073368 http://dx.doi.org/10.4161/onci.24754 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Bowdish, Dawn ME
Myeloid-derived suppressor cells, age and cancer
title Myeloid-derived suppressor cells, age and cancer
title_full Myeloid-derived suppressor cells, age and cancer
title_fullStr Myeloid-derived suppressor cells, age and cancer
title_full_unstemmed Myeloid-derived suppressor cells, age and cancer
title_short Myeloid-derived suppressor cells, age and cancer
title_sort myeloid-derived suppressor cells, age and cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782016/
https://www.ncbi.nlm.nih.gov/pubmed/24073368
http://dx.doi.org/10.4161/onci.24754
work_keys_str_mv AT bowdishdawnme myeloidderivedsuppressorcellsageandcancer