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Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
Tissue-resident macrophages can develop from circulating adult monocytes or from primitive yolk sac–derived macrophages. The precise ontogeny of alveolar macrophages (AMFs) is unknown. By performing BrdU labeling and parabiosis experiments in adult mice, we found that circulating monocytes contribut...
Autores principales: | Guilliams, Martin, De Kleer, Ismé, Henri, Sandrine, Post, Sijranke, Vanhoutte, Leen, De Prijck, Sofie, Deswarte, Kim, Malissen, Bernard, Hammad, Hamida, Lambrecht, Bart N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782041/ https://www.ncbi.nlm.nih.gov/pubmed/24043763 http://dx.doi.org/10.1084/jem.20131199 |
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