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A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma actively remodels the transcriptome of its hosting cells with profound and coupled impact on the host immune response....
Autores principales: | Braun, Laurence, Brenier-Pinchart, Marie-Pierre, Yogavel, Manickam, Curt-Varesano, Aurélie, Curt-Bertini, Rose-Laurence, Hussain, Tahir, Kieffer-Jaquinod, Sylvie, Coute, Yohann, Pelloux, Hervé, Tardieux, Isabelle, Sharma, Amit, Belrhali, Hassan, Bougdour, Alexandre, Hakimi, Mohamed-Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782045/ https://www.ncbi.nlm.nih.gov/pubmed/24043761 http://dx.doi.org/10.1084/jem.20130103 |
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